The New Year is in full swing and for millions of people around the world, it means it's time for healthy eating and losing weight. This is often a bigger challenge than we think. It took time to put on excess body weight, and (you guessed it) it will take time to get rid of it.
Only by getting your nutrition and exercise regimen on track will you get the results you want. Supplements can help you balance the weight loss process and/or make it look less heavy. There are many supplements that have been found to support weight loss. We've taken the best of those ingredients and put them together in our best-selling thermogenic weight loss product - THERMOFUEL.
What supplements are in THERMOFUEL?
Acetyl L-Carnitine Carnitine
Acetyl L-Carnitine Carnitine (ALCAR) is an ingredient that has long been synonymous with fat loss. This is because carnitine plays an essential role in the body's ability to burn fat for fuel (a process known as beta-oxidation). Anyone who has ever dieted to lose fat can tell you that attention spans decrease, as do mental and physical stamina. In addition to supporting fat burning, ALCAR can also help reduce feelings of fatigue, giving you more energy to train harder, ultimately helping you burn more calories!
Green tea extract
Green tea extract is packed with beneficial bio-active compounds, including antioxidants, phenols and catechins - the most well-known catechin being EGCG. In fact, consumption of green tea (as a drink or dietary supplement) has been found to support the following:
- Increased levels of fat oxidation (i.e. fat burning)
- Improved blood flow
- Greater insulin sensitivity
- Improved mood
- Cardiovascular health through a reduction in blood pressure In addition, studies have shown that green tea extract and EGCG increase energy expenditure both at rest and during exercise and improve athletic performance. Finally, studies indicate that green tea extract supplementation may help to:
- Reduce body fat and waist circumference
- Limit calorie intake during meals
Tyrosine is an amino acid that serves as a building block for important neurotransmitters and cholamines, including dopamine and norepinephrine. Dopamine affects mood, motivation, focus, decision making and motor control. As most dieters can attest, mood and motivation often decline over time. L-Tyrosine supplementation may help prevent the normal drop in dopamine that occurs during stressful situations or when you switch between cognitively demanding tasks.
Caffeine is the perfect stimulant, but it also has thermogenic and appetite-suppressing effects. In fact, studies have shown that caffeine intake can achieve the following:
- Increase energy consumption
- Stimulation of lipolysis (the “liberation” of stored fatty acids)
- Improving fat oxidation (“fat burning”) during exercise
- Reduce appetite
- Delay the onset of fatigue, which can help you with your workouts, ultimately leading to greater calorie burn.
Banana leaf extract
The leaves contain more than 40 bioactive substances, but the most important one is corosolic acid. Human studies have shown that corosolic acid can help lower blood sugar within 60 minutes. In addition, banana leaf extract and corosolic acid can help to:
- Improve the cellular uptake of glucose
- Support stable blood sugar levels
- Reduce the digestion of sucrose and starch (which can help reduce the amount of carbohydrates and total calories consumed by a meal)
- Decrease gluconeogenesis
- Regulate lipid metabolism
Research from 2019 also indicates that compounds in banana leaf extract may inhibit the formation of fat cells (adipogenesis) and the formation of fat molecules (lipogenesis).
Cayenne pepper is a fiery, palate-energizing chili pepper used to add a burst of flavor and heat to various culinary creations and is a fundamental ingredient of New Orleans cuisine. In addition to enhancing the flavor of food, the spicy pepper also offers some weight loss benefits. Capsaicin, the alkaloid that gives chili peppers their bite, binds directly to the TRPV1 receptor, releasing norepinephrine, which is great for boosting brown fat thermogenesis. Additional research papers show that:
- Daily energy consumption is increased
- Appetite is reduced
- Weight loss is promoted by the release of serotonin, a hunger suppressing hormone, in the gut
Theobromine is a cousin of caffeine found in several foods, especially dark chocolate. Theobromine can help prolong the energy boost from caffeine. Theobromine is also known to have respiratory benefits, allowing you to work out longer and harder (i.e. not get out of breath) during intense exercise sessions, ultimately allowing you to burn more calories and lose weight faster!
- Dhitavat S, Ortiz D, Shea TB, Rivera ER. Acetyl-L-carnitine protects against amyloid-beta neurotoxicity: roles of oxidative buffering and ATP levels. Neurochem Res. 2002 Jun;27(6):501-5. doi: 10.1023/a:1019800703683. PMID: 12199155.
- Vermeulen RC, Scholte HR. Exploratory open label, randomized study of acetyl- and propionylcarnitine in chronic fatigue syndrome. Psychosom Med. 2004 Mar-Apr;66(2):276-82. doi: 10.1097/01.psy.0000116249.60477.e9. PMID: 15039515.
- Hursel, R., et al. “ The Effects of Catechin Rich Teas and Caffeine on Energy Expenditure and Fat Oxidation: A Meta-Analysis .” Obesity Reviews, vol. 12, no. 7, 2 Mar. 2011, p. e573–e581, 10.1111/j.1467-789x.2011.00862.x
- Ras, Rouyanne T., et al. “ Tea Consumption Enhances Endothelial-Dependent Vasodilation; a Meta-Analysis s.” PLoS ONE, Vol. 6, no. 3, 4 Mar. 2011, p. e16974, 10.1371/journal.pone.0016974
- Hsu, Chung-Hua, et al. “ Does Supplementation with Green Tea Extract Improve Insulin Resistance in Obese Type 2 Diabetics? A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial .” Alternative Medicine Review: A Journal of Clinical Therapeutic, vol. 16, no. 2, 1 June 2011, pp. 157–163
- Venables, Michelle C, et al. “ Green Tea Extract Ingestion, Fat Oxidation, and Glucose Tolerance in Healthy Humans. "The American Journal of Clinical Nutrition, vol. 87, no. 3, 1 Mar. 2008, p. 778–784, 10.1093/ajcn/87.3.778
- Brown, A. Louise, et al. “ Effects of Dietary Supplementation with the Green Tea Polyphenol Epigallocatechin-3-Gallate on Insulin Resistance and Associated Metabolic Risk Factors: Randomized Controlled Trial .” British Journal of Nutrition, vol. 101, no. 6, 19 Aug. 2008, p. 886–894, 10.1017/s0007114508047727
- Boschmann M, Thielecke F. The effects of epigallocatechin-3-gallate on thermogenesis and fat oxidation in obese men: a pilot study . J Am Coll Nutr. 2007;26(4):389S-395S.
- Auvichayapat P, Prapochanung M, Tunkamnerdthai O, et al. Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial . Physiol Behav. 2008;93(3):486-491. doi:http://dx.doi.org/10.1016/j.physbeh.2007.10.009.
- Hodgson AB, Randell RK, Jeukendrup AE. The Effect of Green Tea Extract on Fat Oxidation at Rest and During Exercise: Evidence of Efficacy and Proposed Mechanisms . Advances in Nutrition. 2013;4(2):129-140. doi:10.3945/an.112.003269.
- Lochocka K, Bajerska J, Glapa A, et al. Green tea extract decreases starch digestion and absorption from a test meal in humans: a randomized, placebo-controlled crossover study. Scientific Reports. 2015;5:12015. doi:10.1038/srep12015.
- Le Masurier M, Oldenzeil W, Lehman C, Cowen P, Sharp T. Effect of acute tyrosine depletion in using a branched chain amino-acid mixture on dopamine neurotransmission in the rat brain. Neuropsychopharmacology. 2006 Feb;31(2):310-7. doi: 10.1038/sj.npp.1300835. PMID: 16034439.
- McTavish SF, Raumann B, Cowen PJ, Sharp T. Tyrosine depletion attenuates the behavioral stimulant effects of amphetamine and cocaine in rats. Eur J Pharmacol. 2001 Jul 20;424(2):115-9. doi: 10.1016/s0014-2999(01)01105-0. PMID: 11476757.
- Sidney J. Stohs, Harry G. Preuss, and Mohd Shara, “ A Review of the Receptor-Binding Properties of p-Synephrine as Related to Its Pharmacological Effects ,” Oxidative Medicine and Cellular Longevity, vol. 2011, Article ID 482973, 9 pages, 2011. doi:10.1155/2011/482973
- Stohs SJ. Safety, Efficacy, and Mechanistic Studies Regarding Citrus aurantium (Bitter Orange) Extract and p‐Synephrine . Phytotherapy Research. 2017;31(10):1463-1474. doi:10.1002/ptr.5879.
- Stohs SJ, Preuss HG, Shara M. A Review of the Human Clinical Studies Involving Citrus aurantium (Bitter Orange) Extract and its Primary Protoalkaloid p-Synephrine . Int J Med Sci 2012; 9(7):527-538. doi:10.7150/ijms.4446.
- Ratamess NA, Bush JA, Kang J, et al. The effects of supplementation with P-Synephrine alone and in combination with caffeine on resistance exercise performance . Journal of the International Society of Sports Nutrition. 2015;12:35. doi:10.1186/s12970-015-0096-5.
- Stohs SJ, Miller H, Kaats GR. A review of the efficacy and safety of banaba (Lagerstroemia speciosa L.) and corosolic acid. Phytother Res. 2012 Mar;26(3):317-24. doi: 10.1002/ptr.3664. Epub 2011 Nov 17. PMID: 22095937.
- Miura T, Takagi S, Ishida T. Management of Diabetes and Its Complications with Banaba (Lagerstroemia speciosa L.) and Corosolic Acid. Evid Based Complement Alternat Med. 2012;2012:871495. doi: 10.1155/2012/871495. Epub 2012 Oct 2. PMID: 23082086; PMCID: PMC3468018.
- Karsono AH, Tandrasasmita OM, Tjandrawinata RR. Bioactive fraction from Lagerstroemia speciosa leaves (DLBS3733) reduces fat droplet by inhibiting adipogenesis and lipogenesis. J Exp Pharmacol. 2019 May 2;11:39-51. doi: 10.2147/JEP.S181642. PMID: 31118835; PMCID: PMC6507403.
- Rigamonti AE, Casnici C, Marelli O, De Col A, Tamini S, Lucchetti E, Tringali G, De Micheli R, Abbruzzese L, Bortolotti M, Cella SG, Sartorio A. Acute administration of capsaicin increases resting energy expenditure in young obese subjects without affecting energy intake, appetite, and circulating levels of orexigenic/anorexigenic peptides. Nut Res. 2018 Apr;52:71-79. doi: 10.1016/j.nutres.2018.02.002. Epub 2018 Feb 10. PMID: 29530622.
- Janssens PL, Hursel R, Westerterp-Plantenga MS. Capsaicin increases sensation of fullness in energy balance, and decreases desire to eat after dinner in negative energy balance. Appetite. 2014 Jun;77:44-9. doi: 10.1016/j.appet.2014.02.018. Epub 2014 Mar 12. PMID: 24630935.
- Martínez-Pinilla E, Oñatibia-Astibia A, Franco R. The relevance of theobromine for the beneficial effects of cocoa consumption. Front Pharmacol. 2015;6:30. Published 2015 Feb 20. doi:10.3389/fphar.2015.00030